Molecular Formula | C21H20O11 |
Molar Mass | 448.38 |
Density | 1.713 |
Melting Point | 260-263℃ |
Boling Point | 864.2±65.0 °C(Predicted) |
Solubility | DMSO, Pyridine, Methanol, Ethanol, etc. |
Appearance | Yellow powder |
pKa | 6.42±0.40(Predicted) |
Storage Condition | 2-8°C |
MDL | MFCD11656133 |
In vitro study | Luteolin 5-O-glucoside, at a non-toxic concentration, inhibits LPS-induced NO production and t-BHP-induced ROS generation in a dose-dependent manner in RAW 264.7 cells. Luteolin 5-O-glucoside also suppresses the expression of iNOS and COX-2 in LPS-stimulated macrophages. |
Reference Show more | 1. Wang, Chu-Yang, et al. "Isolation of wheat mutants with higher grain phenolics to enhance anti-oxidant potential." Food chemistry 303 (2020): 125363.https://doi.org/10.1016/j.foodchem.2019.125363 2. Valkó, Klára. "Application of high-performance liquid chromatography based measurements of lipophilicity to model biological distribution." Journal of chromatography A 1037.1-2 (2004): 299-310.https://doi.org/10.1016/j.chroma.2003.10.084 3. Valkó, Klára. "Application of high-performance liquid chromatography based measurements of lipophilicity to model biological distribution." Journal of chromatography A 1037.1-2 (2004): 299-310.https://doi.org/10.1016/j.chroma.2003.10.084 4. [IF=4.411] Jifeng Gu et al."Application of High-Performance Liquid Chromatography Coupled with Linear Ion Trap Quadrupole Orbitrap Mass Spectrometry for Qualitative and Quantitative Assessment of Shejin-Liyan Granule Supplements."Molecules. 2018 Apr;23(4):884 5. [IF=7.514] Chu-Yang Wang et al."Isolation of wheat mutants with higher grain phenolics to enhance anti-oxidant potential."Food Chem. 2020 Jan;303:125363 6. [IF=6.023] Maiquan Li et al."Discovery of Keap1−Nrf2 small−molecule inhibitors from phytochemicals based on molecular docking."Food Chem Toxicol. 2019 Nov;133:110758 |
Plant Source: | honeysuckle |
biological activity | luciolin 5-O-glucoside is from Circle maackii and has anti-inflammatory activity. Luciolin 5-O-glucoside inhibited LPS-induced NO production and t-BHP induced ROS production. Luciolin 5-O-glucoside acts on macrophages and also inhibits iNOS and COX-2 expression. |